Welcome to the Natural Products Navigator

NP Navigator is a freely available intuitive online tool for visualization and navigation through the chemical space of NPs and NP-like molecules. It is based on the hierarchical ensemble of chemical maps featuring NPs from the COlleCtion of Open NatUral producTs (COCONUT), bioactive compounds from ChEMBL and commercially available molecules from ZINC.

NP Navigator allows to efficiently analyze different aspects of NPs - chemotype distribution, physicochemical properties, biological activity and commercial availability of NPs. The latter concerns not only purchasable NPs but also their close or pseudo-NPs.

NP Navigator can be used for different purposes:
• chemical space analysis;
• NP-like libraries comparison;
• searching for the NP-analogues of the compound of interest;
• analysis of the biological activity of NPs.