Welcome to the Lead-Like Tangible chemical space Navigator

Lead-Like Tangible Navigator is a freely available intuitive online tool for visualization and navigation through the chemical space of Lead-Like Tangible molecules. It is based on the hierarchical ensemble of chemical maps featuring Lead-Like Tangible compounds from the COlleCtion of Open NatUral producTs (COCONUT), bioactive compounds from ChEMBL and commercially available molecules from ZINC.

Lead-Like Tangible Navigator allows to efficiently analyze different aspects of Lead-Like Tangible compounds - chemotype distribution, physicochemical properties, biological activity and commercial availability of Lead-Like Tangible compounds. The latter concerns not only purchasable Lead-Like Tangible compounds but also their close or pseudo-Lead-Like Tangible compounds.

Lead-Like Tangible Navigator can be used for different purposes:
• chemical space analysis;
• Lead-Like Tangible libraries comparison;
• searching for the Lead-Like Tangible compounds-analogues of the compound of interest;
• analysis of the biological activity of Lead-Like Tangible compounds.