Welcome to the Lead-Like In-Stock chemical space Navigator

Lead-Like In-Stock Navigator is a freely available intuitive online tool for visualization and navigation through the chemical space of Lead-Like In-Stock molecules. It is based on the hierarchical ensemble of chemical maps featuring Lead-Like In-Stock compounds from the COlleCtion of Open NatUral producTs (COCONUT), bioactive compounds from ChEMBL and commercially available molecules from ZINC.

Lead-Like In-Stock Navigator allows to efficiently analyze different aspects of Lead-Like In-Stock compounds - chemotype distribution, physicochemical properties, biological activity and commercial availability of Lead-Like In-Stock compounds. The latter concerns not only purchasable Lead-Like In-Stock compounds but also their close or pseudo-Lead-Like In-Stock compounds.

Lead-Like In-Stock Navigator can be used for different purposes:
• chemical space analysis;
• Lead-Like In-Stock libraries comparison;
• searching for the Lead-Like In-Stock compounds-analogues of the compound of interest;
• analysis of the biological activity of Lead-Like In-Stock compounds.